Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 5/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL331135 | 0.85 | MIF (0.48) | MIFTRPA1CYP2E1CYP2A6HIF1A | |
| SCHEMBL3593474 | 0.80 | MIF (0.39) | MIFTRPA1CYP2E1CYP2A6HIF1A | |
| SCHEMBL8764230 | 0.78 | MEN1 (0.64) | MEN1KMT2ACYP2A6MMP13MMP9 | |
| Water SCHEMBL27556954 | 0.78 | MIF (0.63) | KMT2AMIFTRPA1HIF1ACYP3A4 | |
| SCHEMBL18567327 | 0.78 | MIF (0.42) | MIFTRPA1CYP2E1CYP2A6HIF1A | |
| SCHEMBL1148243 | 0.76 | TAAR1 (0.45) | MIFTRPA1CYP2E1CYP2A6HIF1A | |
| SCHEMBL1846505 | 0.76 | MIF (0.66) | MIFTRPA1CYP2E1CYP2A6HIF1A | |
| SCHEMBL11253670 | 0.76 | CYP2A6 (0.45) | MEN1KMT2AMIFTRPA1CYP2E1 | |
| SCHEMBL1844610 | 0.76 | TAAR1 (0.45) | MIFTRPA1CYP2E1CYP2A6HIF1A | |
| SCHEMBL895269 | 0.76 | TAAR1 (0.45) | MIFTRPA1CYP2E1CYP2A6HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504434-B2 | Dimeric compounds and their use as anti-viral agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2009-03-17 | — | — | US | disclosed |