Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | APP | P05067 | 3/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13908743 | 0.88 | APP (0.47) | MAPTAPPHDAC3HDAC1HDAC6 | |
| SCHEMBL12668746 | 0.81 | APP (0.52) | MAPTAPPHDAC3HDAC1HDAC6 | |
| SCHEMBL12667837 | 0.81 | APP (0.48) | MAPTAPPHDAC3HDAC1HDAC6 | |
| SCHEMBL12667832 | 0.78 | APP (0.54) | MAPTAPPATG4BMEN1LMNA | |
| SCHEMBL12667839 | 0.77 | APP (0.53) | MAPTAPPATG4B | |
| SCHEMBL12667824 | 0.77 | APP (0.53) | MAPTAPPHDAC3HDAC1HDAC6 | |
| SCHEMBL17320723 | 0.77 | MAPT (0.55) | MAPTAPPATG4BMEN1NPC1 | |
| SCHEMBL12668761 | 0.76 | APP (0.52) | MAPTAPPHDAC3HDAC1HDAC6 | |
| SCHEMBL12667826 | 0.76 | APP (0.54) | MAPTAPPHDAC3HDAC1HDAC6 | |
| SCHEMBL13327539 | 0.75 | MEN1 (0.41) | MAPTHDAC3HDAC1HDAC6HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009037348-A1 | INDOLINIUM-DERIVED THIOL/DISULFIDE DYE, DYE COMPOSITION COMPRISNG THIS DYE, PROCESS FOR LIGHTENING KERATIN MATERIALS USING THIS DYE | L'OREAL (FR) | 2009-03-26 | — | — | WO | disclosed |