Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCD | Q05655 | 1/20 | 0.67 |
| ▸ | CETP | P11597 | 1/20 | 0.65 |
| ▸ | PTGES | O14684 | 2/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.62 |
| ▸ | CES2 | O00748 | 1/20 | 0.62 |
| ▸ | TOP2A | P11388 | 1/20 | 0.62 |
| ▸ | CES1 | P23141 | 1/20 | 0.62 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | NT5E | P21589 | 6/20 | 0.56 |
| ▸ | PRKCG | P05129 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6741284 | 0.94 | PRKCD (0.75) | PRKCDCETPPTGESPTPN1CES2 | |
| SCHEMBL7746354 | 0.90 | PRKCD (0.81) | PRKCDCETPPTGESPTPN1CES2 | |
| SCHEMBL5956717 | 0.90 | PRKCD (0.81) | PRKCDCETPPTGESPTPN1CES2 | |
| SCHEMBL6741278 | 0.90 | PRKCD (0.81) | PRKCDCETPPTGESPTPN1CES2 | |
| SCHEMBL4659804 | 0.90 | PRKCD (0.67) | PRKCDCETPPTGESPTPN1CES2 | |
| SCHEMBL5956497 | 0.90 | PRKCD (0.67) | PRKCDCETPPTGESPTPN1CES2 | |
| SCHEMBL15496672 | 0.89 | CETP (0.69) | PRKCDCETPPTGESPTPN1CES2 | |
| Hydrochloric Acid SCHEMBL4660172 | 0.89 | PRKCD (0.66) | PRKCDCETPPTGESPTPN1CES2 | |
| SCHEMBL5956741 | 0.89 | CETP (0.82) | PRKCDCETPPTGESPTPN1CES2 | |
| SCHEMBL564481 | 0.89 | CETP (0.69) | PRKCDCETPPTGESPTPN1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8586569-B2 | Betulonic and betulinic acid derivatives | Leunis, Jean-Claude (BE) | 2013-11-19 | — | — | US | disclosed |
| US-20090068257-A1 | BETULONIC AND BETULINIC ACID DERIVATIVES | JEAN-CLAUDE LEUNIS (BE) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090068257-A1 | BETULONIC AND BETULINIC ACID DERIVATIVES | BET1, PGGT1B, PAG1 | PRKCD 2306/4885CETP 2393/4885PTGES 950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.