Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 14/20 | 0.75 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13910845 | 0.93 | GSK3B (0.83) | GSK3B | |
| SCHEMBL14063491 | 0.91 | GSK3B (0.76) | GSK3BBACE1 | |
| SCHEMBL13910440 | 0.91 | GSK3B (0.86) | GSK3B | |
| SCHEMBL13910326 | 0.91 | GSK3B (0.82) | GSK3B | |
| SCHEMBL13722107 | 0.89 | GSK3B (0.60) | GSK3BBACE1KMOEGFR | |
| SCHEMBL13910493 | 0.87 | GSK3B (0.79) | GSK3B | |
| SCHEMBL13910070 | 0.87 | GSK3B (0.73) | GSK3BBACE1 | |
| SCHEMBL4034257 | 0.86 | GSK3B (1.00) | GSK3B | |
| SCHEMBL13910454 | 0.86 | GSK3B (0.72) | GSK3B | |
| SCHEMBL4028435 | 0.86 | GSK3B (1.00) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1427720-B1 | 3-SUBSTITUTED-4-PYRIMIDONE DERIVATIVES | MITSUBISHI TANABE PHARMA CORP (JP) | 2009-03-04 | — | — | EP | disclosed |
| US-7427615-B2 | 3-substituted-4-pyrimidone derivatives | MITSUBISHI PHARMA CORPORATION (JP) | 2008-09-23 | — | — | US | disclosed |
| US-7427615-B2 | 3-substituted-4-pyrimidone derivatives | MITSUBISHI PHARMA CORPORATION (JP) | 2008-09-23 | — | — | US | disclosed |