Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 18/20 | 0.78 |
| ▸ | CDC7 | O00311 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13910844 | 0.98 | GSK3B (0.81) | GSK3B | |
| SCHEMBL14063490 | 0.93 | GSK3B (0.74) | GSK3B | |
| SCHEMBL13910517 | 0.90 | GSK3B (0.72) | GSK3B | |
| SCHEMBL13910357 | 0.89 | GSK3B (0.71) | GSK3B | |
| SCHEMBL13910399 | 0.88 | GSK3B (0.79) | GSK3B | |
| SCHEMBL13910847 | 0.88 | GSK3B (0.70) | GSK3B | |
| SCHEMBL13910499 | 0.88 | GSK3B (0.70) | GSK3B | |
| SCHEMBL13722387 | 0.88 | GSK3B (0.67) | GSK3B | |
| SCHEMBL13721913 | 0.88 | GSK3B (0.61) | GSK3B | |
| SCHEMBL13910490 | 0.88 | GSK3B (0.69) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1427720-B1 | 3-SUBSTITUTED-4-PYRIMIDONE DERIVATIVES | MITSUBISHI TANABE PHARMA CORP (JP) | 2009-03-04 | — | — | EP | disclosed |
| US-7427615-B2 | 3-substituted-4-pyrimidone derivatives | MITSUBISHI PHARMA CORPORATION (JP) | 2008-09-23 | — | — | US | disclosed |
| US-7427615-B2 | 3-substituted-4-pyrimidone derivatives | MITSUBISHI PHARMA CORPORATION (JP) | 2008-09-23 | — | — | US | disclosed |