Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 20/20 | 0.79 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13913582 | 0.88 | ADORA1 (1.00) | ADORA1ADORA2BADORA3 | |
| SCHEMBL13913670 | 0.87 | ADORA1 (1.00) | ADORA1ADORA2BADORA3 | |
| SCHEMBL13913698 | 0.85 | ADORA1 (0.81) | ADORA1ADORA2BADORA3 | |
| SCHEMBL13913664 | 0.84 | ADORA1 (0.58) | ADORA1ADORA2BADORA3 | |
| SCHEMBL13913641 | 0.84 | RET (0.63) | ADORA1ADORA2BADORA3 | |
| SCHEMBL13913642 | 0.83 | ADORA1 (0.58) | ADORA1ADORA2BADORA3 | |
| SCHEMBL13914106 | 0.83 | ADORA1 (0.73) | ADORA1ADORA2B | |
| SCHEMBL13913872 | 0.82 | ADORA1 (0.76) | ADORA1ADORA2B | |
| SCHEMBL13914449 | 0.82 | RET (0.61) | ADORA1 | |
| SCHEMBL13914453 | 0.81 | RET (0.74) | ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504421-B2 | Substituted 2-thio-3,5-dicyano-4-aryl-6-aminopyridines and their use | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-03-17 | — | — | US | disclosed |
| US-7504421-B2 | Substituted 2-thio-3,5-dicyano-4-aryl-6-aminopyridines and their use | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-03-17 | — | — | US | disclosed |