Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 19/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.50 |
| ▸ | GSK3A | P49840 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8342890 | 0.90 | GSK3B (0.68) | GSK3BCYP2D6CYP1A2CYP3A4CSNK1A1 | |
| SCHEMBL8342937 | 0.90 | GSK3B (0.59) | GSK3BCYP2D6CYP1A2CYP3A4CSNK1A1 | |
| SCHEMBL13915174 | 0.89 | GSK3B (0.48) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL13917304 | 0.87 | GSK3B (0.60) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL8344282 | 0.86 | GSK3B (0.59) | GSK3B | |
| SCHEMBL13917305 | 0.85 | GSK3B (0.53) | GSK3BCYP2D6CYP1A2CYP3A4CSNK1A1 | |
| SCHEMBL88187 | 0.85 | GSK3B (0.53) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL497065 | 0.85 | GSK3B (0.72) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL8342393 | 0.85 | GSK3B (0.72) | GSK3B | |
| SCHEMBL13917090 | 0.84 | GSK3B (0.75) | GSK3BCYP2D6CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504411-B2 | 2,3,6-Trisubstituted-4-pyrimidone derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-03-17 | — | — | US | disclosed |
| US-7504411-B2 | 2,3,6-Trisubstituted-4-pyrimidone derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-03-17 | — | — | US | disclosed |