SCHEMBL13918367

SCHEMBL13918367

CCCCCCCOc1ccc(CCCOc2ccc(C(=O)O)cc2C(=O)NC2CCCC(C(=O)O)C2)cc1

nearest known ligand 0.86

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYSLTR2 Q9NS75 2/20 0.86
S1PR5 Q9H228 8/20 0.46
TP53 P04637 1/20 0.44
TSHR P16473 1/20 0.44
PLA2G4B P0C869 2/20 0.44
S1PR1 P21453 5/20 0.43
S1PR3 Q99500 4/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13918365 1.00 CYSLTR2 (0.86) CYSLTR2S1PR5TP53TSHRPLA2G4B
SCHEMBL13918370 1.00 CYSLTR2 (0.86) CYSLTR2S1PR5TP53TSHRPLA2G4B
SCHEMBL13918314 0.94 CYSLTR2 (0.80) CYSLTR2S1PR5
SCHEMBL4508651 0.93 CYSLTR2 (0.82) CYSLTR2S1PR5
SCHEMBL4512506 0.92 CYSLTR2 (1.00) CYSLTR2PLA2G4BS1PR1S1PR3
SCHEMBL29438768 0.92 CYSLTR2 (1.00) CYSLTR2PLA2G4BS1PR1S1PR3
SCHEMBL13918307 0.92 CYSLTR2 (0.80) CYSLTR2
SCHEMBL4527529 0.92 CYSLTR2 (0.95) CYSLTR2S1PR5PLA2G4BS1PR1S1PR3
SCHEMBL13932996 0.92 CYSLTR2 (0.98) CYSLTR2PLA2G4BS1PR1S1PR3
SCHEMBL4509695 0.91 CYSLTR2 (0.87) CYSLTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7498460-B2 Isophthalic acid derivatives BAYER HEALTHCARE AG (DE) 2009-03-03 US disclosed
US-7498460-B2 Isophthalic acid derivatives BAYER HEALTHCARE AG (DE) 2009-03-03 US disclosed