Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 12/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12132140 | 0.94 | KCNA3 (0.76) | KCNA3 | |
| SCHEMBL12132141 | 0.90 | KCNA3 (0.80) | KCNA3 | |
| SCHEMBL4482527 | 0.90 | KCNA3 (1.00) | KCNA3 | |
| SCHEMBL10632689 | 0.90 | KCNA3 (0.80) | KCNA3 | |
| SCHEMBL10821323 | 0.90 | KCNA3 (0.78) | KCNA3 | |
| SCHEMBL4495556 | 0.89 | KCNA3 (1.00) | KCNA3 | |
| SCHEMBL4471891 | 0.89 | KCNA3 (1.00) | KCNA3 | |
| SCHEMBL13920862 | 0.88 | KCNA3 (1.00) | KCNA3 | |
| SCHEMBL13920855 | 0.88 | KCNA3 (1.00) | KCNA3 | |
| SCHEMBL3601227 | 0.87 | KCNA3 (0.83) | KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7507839-B2 | Therapeutic ion channel blocking agents and methods of use thereof | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2009-03-24 | — | — | US | disclosed |
| US-7507839-B2 | Therapeutic ion channel blocking agents and methods of use thereof | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2009-03-24 | — | — | US | disclosed |