Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.75 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4521894 | 0.98 | CYSLTR2 (0.78) | CYSLTR2RAB9AMAPTMEN1KMT2A | |
| SCHEMBL4524350 | 0.96 | CYSLTR2 (0.74) | CYSLTR2RAB9AMAPTMEN1KMT2A | |
| SCHEMBL4521604 | 0.94 | CYSLTR2 (0.68) | CYSLTR2RAB9AMAPTMEN1KMT2A | |
| SCHEMBL4518460 | 0.94 | CYSLTR2 (0.69) | CYSLTR2RAB9AMAPTMEN1KMT2A | |
| SCHEMBL13918309 | 0.94 | CYSLTR2 (0.68) | CYSLTR2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL13918341 | 0.94 | CYSLTR2 (0.70) | CYSLTR2RAB9AMAPTMEN1KMT2A | |
| SCHEMBL13918330 | 0.93 | CYSLTR2 (0.68) | CYSLTR2RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL4520534 | 0.93 | CYSLTR2 (0.68) | CYSLTR2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL13918239 | 0.92 | CYSLTR2 (0.73) | CYSLTR2RAB9AMAPTMEN1KMT2A | |
| SCHEMBL4522056 | 0.92 | CYSLTR2 (0.65) | CYSLTR2RAB9AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498460-B2 | Isophthalic acid derivatives | BAYER HEALTHCARE AG (DE) | 2009-03-03 | — | — | US | disclosed |
| EP-1572628-B1 | ISOPHTALIC ACID DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-07-25 | — | — | EP | disclosed |