Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.63 |
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.42 |
| ▸ | DGKA | P23743 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13933135 | 0.90 | CYP3A4 (0.61) | CYP3A4TSHRTDP1ATMALDH1A1 | |
| SCHEMBL13933107 | 0.88 | CYP3A4 (0.59) | CYP3A4TSHRTDP1ATMALDH1A1 | |
| SCHEMBL13612297 | 0.85 | CYP3A4 (0.64) | CYP3A4TSHRTDP1ATMALDH1A1 | |
| SCHEMBL13933127 | 0.84 | CYP3A4 (0.57) | CYP3A4TSHRTDP1ATMALDH1A1 | |
| SCHEMBL14566052 | 0.82 | CYP3A4 (0.64) | CYP3A4TSHRTDP1ATMALDH1A1 | |
| SCHEMBL13571781 | 0.82 | TSHR (0.82) | CYP3A4TSHRTDP1ATMALDH1A1 | |
| SCHEMBL13571597 | 0.82 | TSHR (0.82) | CYP3A4TSHRTDP1ATMALDH1A1 | |
| SCHEMBL17781790 | 0.82 | TSHR (0.82) | CYP3A4TSHRTDP1ATMALDH1A1 | |
| SCHEMBL9234776 | 0.82 | TSHR (0.82) | CYP3A4TSHRTDP1ATMALDH1A1 | |
| SCHEMBL8358615 | 0.82 | TSHR (0.82) | CYP3A4TSHRTDP1ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7485604-B2 | Lubricant composition and method for using and preparing thereof | FUJIFILM CORPORATION (JP) | 2009-02-03 | — | — | US | disclosed |