Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 19/20 | 0.69 |
| ▸ | PPARA | Q07869 | 18/20 | 0.69 |
| ▸ | PPARG | P37231 | 5/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4114820 | 0.92 | PPARD (0.82) | PPARDPPARAPPARG | |
| SCHEMBL4109033 | 0.92 | PPARD (0.81) | PPARDPPARAPPARG | |
| SCHEMBL4109769 | 0.91 | PPARD (0.82) | PPARDPPARAPPARG | |
| SCHEMBL13934531 | 0.90 | PPARD (0.72) | PPARDPPARAPPARG | |
| SCHEMBL14527810 | 0.89 | PPARD (0.70) | PPARDPPARAPPARG | |
| SCHEMBL4102971 | 0.89 | PPARD (0.82) | PPARDPPARAPPARG | |
| SCHEMBL4114763 | 0.89 | PPARD (0.82) | PPARDPPARAPPARG | |
| SCHEMBL4114448 | 0.86 | PPARD (0.83) | PPARDPPARAPPARG | |
| SCHEMBL4114730 | 0.86 | PPARD (0.83) | PPARDPPARAPPARG | |
| SCHEMBL5892509 | 0.83 | PPARD (0.67) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498351-B2 | 4-((Phenoxyalkyl)thio)-phenoxyacetic acids and analogs | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-03-03 | — | — | US | disclosed |