Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 19/20 | 0.81 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4123493 | 1.00 | PTGDR2 (0.81) | PTGDR2MEN1KMT2A | |
| SCHEMBL4126934 | 1.00 | PTGDR2 (0.81) | PTGDR2MEN1KMT2A | |
| SCHEMBL14502239 | 1.00 | PTGDR2 (0.81) | PTGDR2MEN1KMT2A | |
| SCHEMBL4128803 | 0.92 | PTGDR2 (0.77) | PTGDR2MEN1KMT2A | |
| SCHEMBL14502240 | 0.92 | PTGDR2 (0.77) | PTGDR2MEN1KMT2A | |
| SCHEMBL4128800 | 0.92 | PTGDR2 (0.77) | PTGDR2MEN1KMT2A | |
| SCHEMBL13776269 | 0.92 | PTGDR2 (0.76) | PTGDR2MEN1KMT2A | |
| SCHEMBL4123783 | 0.91 | PTGDR2 (0.84) | PTGDR2MEN1KMT2A | |
| SCHEMBL5504942 | 0.91 | PTGDR2 (0.84) | PTGDR2MEN1KMT2A | |
| SCHEMBL4123784 | 0.91 | PTGDR2 (0.84) | PTGDR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504508-B2 | PGD2 receptor antagonists for the treatment of inflammatory diseases | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2009-03-17 | — | — | US | disclosed |