Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 14/20 | 0.82 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.60 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.60 |
| ▸ | KIT | P10721 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4484850 | 0.90 | FGFR2 (1.00) | FGFR2PDGFRBPDGFRAKITKDR | |
| SCHEMBL5826095 | 0.86 | FGFR2 (0.74) | FGFR2PDGFRBPDGFRAKITKDR | |
| SCHEMBL7489910 | 0.85 | FGFR2 (0.76) | FGFR2PDGFRBPDGFRAKITKDR | |
| SCHEMBL8553216 | 0.85 | FGFR2 (0.72) | FGFR2PDGFRBPDGFRAKITKDR | |
| SCHEMBL4473682 | 0.85 | FGFR2 (0.84) | FGFR2PDGFRBPDGFRAKITKDR | |
| SCHEMBL4472020 | 0.85 | FGFR2 (1.00) | FGFR2PDGFRBPDGFRAKITKDR | |
| SCHEMBL842293 | 0.83 | FGFR2 (1.00) | FGFR2PDGFRBPDGFRAKITKDR | |
| SCHEMBL29574069 | 0.83 | FGFR2 (1.00) | FGFR2PDGFRBPDGFRAKITKDR | |
| SCHEMBL4476013 | 0.83 | FGFR2 (0.80) | FGFR2PDGFRBPDGFRAKITKDR | |
| SCHEMBL4473353 | 0.83 | FGFR2 (0.80) | FGFR2PDGFRBPDGFRAKITKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7495104-B2 | Quinoline or quinazoline derivatives inhibiting auto-phosphorylation of fibroblast growth factor receptors | KIRIN BEER KABUSHIKI KAISHA (JP) | 2009-02-24 | — | — | US | disclosed |
| US-7495104-B2 | Quinoline or quinazoline derivatives inhibiting auto-phosphorylation of fibroblast growth factor receptors | KIRIN BEER KABUSHIKI KAISHA (JP) | 2009-02-24 | — | — | US | disclosed |