Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 17/20 | 1.00 |
| ▸ | KDR | P35968 | 2/20 | 0.59 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.59 |
| ▸ | KIT | P10721 | 1/20 | 0.59 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 2/20 | 0.54 |
| ▸ | MET | P08581 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4468252 | 1.00 | FGFR2 (1.00) | FGFR2KDRPDGFRBKITPDGFRA | |
| SCHEMBL4473687 | 1.00 | FGFR2 (1.00) | FGFR2KDRPDGFRBKITPDGFRA | |
| SCHEMBL13936714 | 1.00 | FGFR2 (1.00) | FGFR2KDRPDGFRBKITPDGFRA | |
| SCHEMBL4486805 | 1.00 | FGFR2 (1.00) | FGFR2KDRPDGFRBKITPDGFRA | |
| SCHEMBL4473689 | 1.00 | FGFR2 (1.00) | FGFR2KDRPDGFRBKITPDGFRA | |
| SCHEMBL4486995 | 0.93 | FGFR2 (0.98) | FGFR2KDRPDGFRBKITPDGFRA | |
| SCHEMBL4471376 | 0.92 | FGFR2 (1.00) | FGFR2KDRPDGFRBKITPDGFRA | |
| SCHEMBL4472099 | 0.92 | FGFR2 (1.00) | FGFR2KDRPDGFRBKITPDGFRA | |
| SCHEMBL4489395 | 0.92 | FGFR2 (0.87) | FGFR2KDRPDGFRBKITPDGFRA | |
| SCHEMBL13936682 | 0.89 | FGFR2 (0.87) | FGFR2KDRPDGFRBKITPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7495104-B2 | Quinoline or quinazoline derivatives inhibiting auto-phosphorylation of fibroblast growth factor receptors | KIRIN BEER KABUSHIKI KAISHA (JP) | 2009-02-24 | — | — | US | disclosed |
| US-7495104-B2 | Quinoline or quinazoline derivatives inhibiting auto-phosphorylation of fibroblast growth factor receptors | KIRIN BEER KABUSHIKI KAISHA (JP) | 2009-02-24 | — | — | US | disclosed |