Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 10/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 3/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13939919 | 0.85 | KDM1A (0.47) | KDM1AMAOAMAOB | |
| SCHEMBL13939519 | 0.81 | KDM1A (0.43) | KDM1AMAOAMAOB | |
| SCHEMBL3871781 | 0.75 | KDM1A (0.45) | DHODHKDM1AMAOAMAOBALPL | |
| SCHEMBL3872607 | 0.74 | ADORA2A (0.48) | DHODHKDM1AKMO | |
| SCHEMBL13939921 | 0.73 | KDM1A (0.41) | KDM1AMAOAMAOB | |
| SCHEMBL3873988 | 0.72 | KDM1A (0.41) | DHODHKDM1AMAOAMAOBHDAC1 | |
| SCHEMBL529220 | 0.72 | KDM1A (0.64) | KDM1AMAOB | |
| SCHEMBL527379 | 0.72 | KDM1A (0.64) | KDM1AMAOB | |
| SCHEMBL529221 | 0.72 | KDM1A (0.64) | KDM1AMAOB | |
| Trifluoroacetic Acid SCHEMBL3871552 | 0.71 | KDM1A (0.57) | KDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904476-B1 | HETEROARYL-SUBSTITUTED AMIDES COMPRISING AN UNSATURATED OR CYCLIC LINKER GROUP, AND THEIR USE AS PHARMACEUTICALS | SANOFI AVENTIS (FR) | 2009-02-25 | — | — | EP | disclosed |
| EP-1741708-A1 | Heteroaryl-substituted amides comprising an unsaturated or cyclic linker group, and their use as pharmaceuticals | Sanofi-Aventis Deutschland GmbH (DE) | 2007-01-10 | — | — | EP | disclosed |