Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 15/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1394185 | 1.00 | HSP90AA1 (0.50) | HSP90AA1HSP90AB1PRKCQTDP1L3MBTL1 | |
| SCHEMBL1394580 | 0.91 | HSP90AA1 (0.51) | HSP90AA1HSP90AB1PRKCQ | |
| SCHEMBL1394581 | 0.91 | HSP90AA1 (0.51) | HSP90AA1HSP90AB1PRKCQ | |
| SCHEMBL1395432 | 0.89 | HSP90AA1 (0.45) | HSP90AA1HSP90AB1PRKCQ | |
| SCHEMBL1395433 | 0.89 | HSP90AA1 (0.45) | HSP90AA1HSP90AB1PRKCQ | |
| SCHEMBL1394440 | 0.82 | HSP90AA1 (0.49) | HSP90AA1HSP90AB1 | |
| SCHEMBL2181668 | 0.82 | PRKCQ (0.37) | HSP90AA1HSP90AB1PRKCQ | |
| SCHEMBL1394663 | 0.80 | AR (0.44) | TDP1L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL1395071 | 0.80 | TDP1 (0.43) | TDP1L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL1394983 | 0.79 | HSP90AA1 (0.46) | HSP90AA1HSP90AB1PRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120010241-A1 | HSP90 INHIBITING INDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING SAME AND USE THEREOF | SANOFI (FR) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010241-A1 | HSP90 INHIBITING INDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING SAME AND USE THEREOF | HSP90AB2P, HSP90AB1, HSP90AA1 | HSP90AA1 3/4885HSP90AB1 2/4885PRKCQ 3826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.