Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13910945 | 0.79 | CA9 (0.41) | TOP2A | |
| SCHEMBL5440871 | 0.79 | CA9 (0.41) | TOP2A | |
| SCHEMBL14374379 | 0.75 | HSD17B10 (0.36) | — | |
| SCHEMBL13910947 | 0.73 | SLC10A1 (0.44) | TOP2A | |
| SCHEMBL14374329 | 0.71 | CA9 (0.42) | TOP2A | |
| SCHEMBL5448119 | 0.71 | CA9 (0.42) | TOP2A | |
| SCHEMBL5446514 | 0.70 | TDP1 (0.42) | — | |
| SCHEMBL14374326 | 0.69 | CA9 (0.41) | TOP2A | |
| SCHEMBL5454240 | 0.69 | CA9 (0.41) | TOP2A | |
| SCHEMBL14399188 | 0.68 | CA9 (0.40) | TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009020732-A1 | LUPANE-TYPE TRITERPENOIDS MODIFIED AT 30-POSITION AND ANALOGUES THEREOF | ADVANCED LIFE SCIENCES, INC. (US) | 2009-02-12 | — | — | WO | disclosed |