SCHEMBL139446

SCHEMBL139446

CCCCCC[CH]c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.47
LMNA P02545 1/20 0.44
CNR1 P21554 2/20 0.44
EGFR P00533 1/20 0.44
SOAT2 O75908 1/20 0.42
SOAT1 P35610 1/20 0.42
EPHX2 P34913 3/20 0.41
FAAH O00519 2/20 0.41
DNM1 Q05193 2/20 0.40
TSHR P16473 2/20 0.39
TP53 P04637 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
MEN1 O00255 1/20 0.39
MAPK1 P28482 1/20 0.39
KMT2A Q03164 1/20 0.39
PKM P14618 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
MAPT P10636 1/20 0.39
CNR2 P34972 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL303162 1.00 TDP1 (0.47) TDP1LMNACNR1EGFRSOAT2
SCHEMBL2125298 1.00 TDP1 (0.47) TDP1LMNACNR1EGFRSOAT2
SCHEMBL303521 1.00 TDP1 (0.47) TDP1LMNACNR1EGFRSOAT2
SCHEMBL302928 1.00 TDP1 (0.47) TDP1LMNACNR1EGFRSOAT2
SCHEMBL303164 1.00 TDP1 (0.47) TDP1LMNACNR1EGFRSOAT2
SCHEMBL302971 1.00 TDP1 (0.47) TDP1LMNACNR1EGFRSOAT2
SCHEMBL304116 1.00 TDP1 (0.47) TDP1LMNACNR1EGFRSOAT2
SCHEMBL302694 1.00 TDP1 (0.47) TDP1LMNACNR1EGFRSOAT2
SCHEMBL5206775 1.00 TDP1 (0.47) TDP1LMNACNR1EGFRSOAT2
SCHEMBL302639 1.00 TDP1 (0.47) TDP1LMNACNR1EGFRSOAT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115838368-B Hydroxamic acid compound and derivative thereof, preparation method, pharmaceutical composition and application 中国药科大学 2024-02-27 CN claimed
CN-115838368-A Oxime acid compound and derivative, preparation method, pharmaceutical composition and application thereof 中国药科大学 2023-03-24 CN claimed
CN-114907363-A Organic compound and organic electroluminescent device 机光科技股份有限公司 2022-08-16 CN claimed
CN-109563431-B Lubricating oil composition, lubricating method, and transmission 出光兴产株式会社 2022-05-03 CN claimed
CN-107963982-B Polyisocyanate composition and isocyanate polymer composition 旭化成株式会社 2021-11-12 CN claimed
CN-105980535-B lubricating oil composition 出光兴产株式会社 2019-07-19 CN claimed
CN-103459452-B Storage-stable polyurethane prepregs made of polyurethane compositions with liquid resin components and molded parts made therefrom EVONIK DEGUSSA GMBH (DE) 2016-11-30 CN claimed
CN-103384719-B Bearing grease IDEMITSU KOSAN CO.,LTD. (JP) 2015-11-25 CN claimed
EP-2786985-A2 Antagonists of the glucagon receptor Metabasis Therapeutics, Inc. (US) 2014-10-08 EP claimed
CN-103459452-A Storage-stable polyurethane prepregs made of polyurethane compositions with liquid resin components and molded parts made therefrom EVONIK DEGUSSA GMBH 2013-12-18 CN claimed
US-5051517-A Reacting a chloroformidine hydrochloride with an oxamohydrazide, forming bonds between carbon and nitrogen and cyclization BAYER AKTIENGESELLSCHAFT (DE) 1991-09-24 US claimed
EP-0431390-A1 Substituted triazolinones BAYER AG (DE) 1991-06-12 EP claimed
EP-0415196-A2 Substituted 4,5-diamino-1,2,4-triazol-3-(thi)ones BAYER AG (DE) 1991-03-06 EP claimed
EP-0412358-A1 3-Amino-5-aminocarbonyl-1,2,4-triazole derivatives BAYER AG (DE) 1991-02-13 EP claimed
EP-0403252-A2 Process for preparation of epoxy esters and intermediates prepared thereby SMITHKLINE BEECHAM CORPORATION (US) 1990-12-19 EP claimed
EP-0399285-A1 Process for the preparation of 3-amino-5-aminocarbonyl-1,2,4-triazole derivatives BAYER AG (DE) 1990-11-28 EP claimed
EP-0332991-A1 Substituted triazoles BAYER AG (DE) 1989-09-20 EP claimed
EP-0298371-A1 Substituted triazolinones BAYER AG (DE) 1989-01-11 EP claimed
EP-0283876-A2 Substituted triazolinones BAYER AG (DE) 1988-09-28 EP claimed
EP-0260689-A2 Naphtholactam quadratic-acid dyes and optical registration materials containing them BASF Aktiengesellschaft (DE) 1988-03-23 EP claimed