Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.84 |
| ▸ | HTR2A | P28223 | 1/20 | 0.84 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.84 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.84 |
| ▸ | HTR1A | P08908 | 4/20 | 0.59 |
| ▸ | HTR7 | P34969 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12124408 | 0.91 | SLC6A2 (1.00) | SLC6A2HTR2ASLC6A4SLC6A3 | |
| SCHEMBL12124505 | 0.91 | SLC6A2 (0.78) | SLC6A2HTR2ASLC6A4SLC6A3HTR1A | |
| SCHEMBL12124491 | 0.90 | SLC6A2 (0.98) | SLC6A2HTR2ASLC6A4SLC6A3 | |
| SCHEMBL12124469 | 0.90 | SLC6A2 (0.98) | SLC6A2HTR2ASLC6A4SLC6A3 | |
| SCHEMBL12124486 | 0.89 | SLC6A2 (0.82) | SLC6A2HTR2ASLC6A4SLC6A3 | |
| SCHEMBL12124445 | 0.89 | SLC6A2 (0.96) | SLC6A2HTR2ASLC6A4SLC6A3 | |
| SCHEMBL12124674 | 0.88 | SLC6A2 (0.93) | SLC6A2HTR2ASLC6A4SLC6A3 | |
| SCHEMBL12124482 | 0.85 | SLC6A2 (0.89) | SLC6A2HTR2ASLC6A4SLC6A3 | |
| SCHEMBL12124635 | 0.85 | SLC6A2 (0.72) | SLC6A2HTR2ASLC6A4SLC6A3HTR1A | |
| SCHEMBL12124503 | 0.85 | SLC6A2 (0.72) | SLC6A2HTR2ASLC6A4SLC6A3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026227-A2 | HIGHLY SELECTIVE SIGMA RECEPTOR LIGANDS | THE UNIVERSITY OF MISSISSIPPI (US) | 2009-02-26 | — | — | WO | disclosed |