Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 9/20 | 0.64 |
| ▸ | C1S | P09871 | 15/20 | 0.57 |
| ▸ | PLG | P00747 | 1/20 | 0.52 |
| ▸ | PLAT | P00750 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6921044 | 0.78 | PLAU (1.00) | PLAUC1SPLGPLATPRSS1 | |
| SCHEMBL7736128 | 0.75 | PLAU (0.70) | PLAUC1SPLGPLATPRSS1 | |
| SCHEMBL7738320 | 0.74 | PLAU (0.69) | PLAUC1SPLGPLATPRSS1 | |
| Hydrochloric Acid SCHEMBL7472212 | 0.74 | PLAU (0.69) | PLAUC1SPLGPLATPRSS1 | |
| SCHEMBL6927284 | 0.73 | C1S (0.75) | PLAUC1SPLGPLATPRSS1 | |
| Hydrochloric Acid SCHEMBL7475045 | 0.73 | PLAU (0.67) | PLAUC1SPLGPLATPRSS1 | |
| SCHEMBL7738277 | 0.73 | C1S (1.00) | PLAUC1SPLGPLATPRSS1 | |
| SCHEMBL6928307 | 0.72 | PLAU (1.00) | PLAUC1S | |
| SCHEMBL6923479 | 0.72 | C1S (1.00) | PLAUC1SPLGPLATPRSS1 | |
| SCHEMBL6920013 | 0.72 | C1S (0.67) | PLAUC1SPLGPLATPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7482376-B2 | Conjugated complement cascade inhibitors | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2009-01-27 | — | — | US | disclosed |
| US-7482376-B2 | Conjugated complement cascade inhibitors | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2009-01-27 | — | — | US | disclosed |