SCHEMBL139466

SCHEMBL139466

CCCCCNC(=S)SSC(=S)NCCCCC

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4A O75164 1/20 0.54
EPHX1 P07099 8/20 0.48
CASP2 P42575 1/20 0.43
ALDH1A1 P00352 1/20 0.42
TSHR P16473 1/20 0.42
ZDHHC20 Q5W0Z9 1/20 0.41
ZDHHC2 Q9UIJ5 1/20 0.41
NAAA Q02083 1/20 0.41
EPHX2 P34913 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29278260 0.98 KDM4A (0.52) KDM4AEPHX1CASP2ZDHHC20ZDHHC2
SCHEMBL3271166 0.98 KDM4A (0.52) KDM4AEPHX1CASP2ZDHHC20ZDHHC2
SCHEMBL381501 0.98 KDM4A (0.52) KDM4AEPHX1CASP2ZDHHC20ZDHHC2
SCHEMBL27805156 0.92 KDM4A (0.64) KDM4AEPHX1CASP2ZDHHC20ZDHHC2
SCHEMBL11034533 0.91 EPHX1 (0.45) KDM4AEPHX1CASP2ALDH1A1TSHR
SCHEMBL28870686 0.88 EPHX1 (0.44) KDM4AEPHX1CASP2ZDHHC20ZDHHC2
SCHEMBL28186673 0.88 EPHX1 (0.44) KDM4AEPHX1CASP2ZDHHC20ZDHHC2
SCHEMBL30957958 0.88 EPHX1 (0.44) KDM4AEPHX1CASP2ZDHHC20ZDHHC2
SCHEMBL22471734 0.88 EPHX1 (0.44) KDM4AEPHX1CASP2ZDHHC20ZDHHC2
SCHEMBL28218765 0.88 EPHX1 (0.44) KDM4AEPHX1CASP2ZDHHC20ZDHHC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 996 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122037329-A Double-network crosslinked carcass rubber composition of cracked carbon black-bio-based liquid rubber and preparation method thereof 中策橡胶集团股份有限公司 2026-05-15 CN claimed
US-20250002615-A1 METHOD FOR PREPARING GRAFT COPOLYMER, GRAFT COPOLYMER AND RESIN COMPOSITION COMPRISING SAME LG CHEM, LTD. (KR) 2025-01-02 US claimed
WO-2024221494-A1 CATALYST, PREPARATION METHOD THEREFOR, AND USE THEREOF 上海凯赛生物技术股份有限公司 2024-10-31 WO claimed
CN-118847119-A Catalyst and preparation method and application thereof 上海凯赛生物技术股份有限公司 2024-10-29 CN claimed
CN-118434796-A Composition for polyurethane foam, foam prepared therefrom and method thereof 迈图高新材料公司 2024-08-02 CN claimed
CN-118206689-A Latex composition for dip molding, method for producing same, and dip molded article produced therefrom 锦湖石油化学株式会社 2024-06-18 CN claimed
WO-2024102364-A1 SYSTEM AND METHOD FOR REMOTE SCREENING AND DIAGNOSIS OF CONTACT ALLERGIES THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2024-05-16 WO claimed
EP-4357380-A1 METHOD FOR MANUFACTURING GRAFT COPOLYMER, GRAFT COPOLYMER, AND RESIN COMPOSITION COMPRISING SAME LG Chem, Ltd. (KR) 2024-04-24 EP claimed
US-11753408-B2 Compounds and method for blocking transmission of malarial parasite THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2023-09-12 US claimed
US-20210246137-A1 COMPOUNDS AND METHOD FOR BLOCKING TRANSMISSION OF MALARIAL PARASITE THE UNITED STATES OF AMERICA,AS REPRESENTED BY THE SECRETARY,DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2021-08-12 US claimed
WO-1996009406-A1 A METHOD FOR IDENTIFYING AND USING COMPOUNDS THAT INACTIVATE HIV-1 AND OTHER RETROVIRUSES BY ATTACKING HIGHLY CONSERVED ZINC FINGERS IN THE VIRAL NUCLEOCAPSID PROTEIN THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1996-03-28 WO claimed
EP-0093500-B1 ROOF COVERING BY MAKING USE OF AN ELASTOMERIC COMPOSITION UNIROYAL CHEMICAL COMPANY, Inc. (US) 1988-06-29 EP claimed
EP-0154437-A2 Substituted dithiocarbamylurea accelerators UNIROYAL CHEMICAL COMPANY, Inc. (US) 1985-09-11 EP claimed
US-4514442-A CURING EPDM AND BUTYL RUBBER MIXES WITH SULFUR AND HEXASULFIDE COMPOUNDS UNIROYAL, INC. (US) 1985-04-30 US claimed
US-4461875-A ETHYLENE-PROPYLENE-NON-CONJUGATED DIENE TERPOLYMER AND/OR BUTYL RUBBER WITH THIURAM HEXASULFIDE, AND SULFUR COMPOUND UNIROYAL, INC. (US) 1984-07-24 US claimed
EP-0093500-A1 Roof covering by making use of an elastomeric composition UNIROYAL CHEMICAL COMPANY, Inc. (US) 1983-11-09 EP claimed
US-4237247-A MERCAPTOTRIAZINE CROSSLINKING AGENT AND A THIURAM SULFIDE ACCELERATOR AND AN ACID ACCEPTOR ALLOW THE USE OF ADDITIVES DURING CURING OSAKA SODA CO. LTD. (JP) 1980-12-02 US claimed
EP-0017751-A1 Process for the production of graft copolymers of polyphenylene oxides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1980-10-29 EP claimed
US-4146689-A SULFUR AND SULFUR-DONOR SANYO TRADING CO., LTD. (JP) 1979-03-27 US claimed
US-4129609-A Method for improving storage stability of epoxy ester thermosetting resins with thiuram compounds NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) 1978-12-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11753408-B2 Compounds and method for blocking transmission of malarial parasite PLK1, HSP90B1, CEP170 KDM4A 2994/4885EPHX1 2195/4885CASP2 275/4885
US-20210246137-A1 COMPOUNDS AND METHOD FOR BLOCKING TRANSMISSION OF MALARIAL PARASITE PLK1, HSP90B1, CEP170 KDM4A 2994/4885EPHX1 2195/4885CASP2 275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.