Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 15/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.52 |
| ▸ | TCF7L2 | Q9NQB0 | 2/20 | 0.52 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.52 |
| ▸ | PDE2A | O00408 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13947568 | 0.93 | HTR2C (0.63) | HTR2CTP53HRH4PDE2A | |
| SCHEMBL13944729 | 0.91 | HTR2C (0.72) | HTR2CTP53CTNNB1TCF7L2HRH4 | |
| SCHEMBL13944359 | 0.90 | HTR2C (0.77) | HTR2CTP53HRH4PDE2A | |
| SCHEMBL13947035 | 0.90 | PDE2A (0.64) | HTR2CTP53HRH4PDE2A | |
| SCHEMBL13943298 | 0.90 | HTR2C (0.61) | HTR2CHRH4PDE2A | |
| SCHEMBL13944731 | 0.89 | HTR2C (0.72) | HTR2CTP53CTNNB1TCF7L2HRH4 | |
| SCHEMBL13944721 | 0.87 | HTR2C (0.74) | HTR2CTP53CTNNB1TCF7L2PDE2A | |
| SCHEMBL13944177 | 0.84 | HTR2C (0.57) | HTR2CTP53CTNNB1TCF7L2HRH4 | |
| SCHEMBL13944192 | 0.82 | HTR2C (0.60) | HTR2CHRH4PDE2A | |
| SCHEMBL13946815 | 0.81 | HTR2C (0.72) | HTR2CHRH4PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2025678-A1 | Pyrazolo[3,4-d]pyrimidine compounds and their use as modulators of protein kinase | Oncalis AG (CH) | 2009-02-18 | — | — | EP | disclosed |