Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 5/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | F3 | P13726 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13044742 | 0.93 | SCN9A (0.35) | PTK2SCN9ALRRK2 | |
| SCHEMBL13947102 | 0.92 | SCN9A (0.34) | PTK2SCN9ALRRK2OPRK1MAPT | |
| SCHEMBL13044788 | 0.89 | PTK2 (0.32) | PTK2SCN9ARIPK1OPRK1 | |
| SCHEMBL13947329 | 0.88 | POLB (0.37) | PTK2MAPTCFTR | |
| SCHEMBL13044756 | 0.86 | SCN9A (0.34) | PTK2SCN9A | |
| SCHEMBL13044704 | 0.85 | SCN9A (0.35) | PTK2SCN9A | |
| SCHEMBL13044744 | 0.85 | SCN9A (0.33) | PTK2SCN9A | |
| SCHEMBL13044802 | 0.85 | SCN9A (0.33) | PTK2SCN9A | |
| SCHEMBL13044814 | 0.85 | SCN9A (0.33) | PTK2SCN9A | |
| SCHEMBL13947023 | 0.84 | SCN9A (0.33) | PTK2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009018656-A1 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-02-12 | — | — | WO | disclosed |