Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 19/20 | 0.55 |
| ▸ | CXCR1 | P25024 | 16/20 | 0.55 |
| ▸ | CCR7 | P32248 | 3/20 | 0.50 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13405676 | 0.86 | CXCR2 (0.55) | CXCR2CXCR1CCR7CCR6 | |
| SCHEMBL13439958 | 0.86 | CXCR2 (0.55) | CXCR2CXCR1CCR7CCR6 | |
| SCHEMBL12262900 | 0.84 | CXCR2 (0.70) | CXCR2CXCR1CCR7CCR6 | |
| SCHEMBL13344815 | 0.82 | CXCR2 (0.63) | CXCR2CXCR1CCR7CCR6 | |
| SCHEMBL13208199 | 0.82 | CXCR2 (0.79) | CXCR2CXCR1CCR7 | |
| SCHEMBL13207093 | 0.81 | CXCR2 (0.61) | CXCR2CXCR1CCR7CCR6 | |
| SCHEMBL13948441 | 0.80 | CXCR2 (0.40) | CXCR2CXCR1CCR7 | |
| SCHEMBL12779729 | 0.79 | CXCR2 (0.60) | CXCR2CXCR1CCR7CCR6 | |
| SCHEMBL14619813 | 0.79 | CXCR2 (0.57) | CXCR2CXCR1CCR7CCR6 | |
| SCHEMBL13345266 | 0.78 | CXCR2 (0.56) | CXCR2CXCR1CCR7CCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1551818-B1 | THIADIAZOLEDIOXIDES AND THIADIAZOLEOXIDES AS CXC- AND CC-CHEMOKINE RECEPTOR LIGANDS | SCHERING CORP (US) | 2009-02-04 | — | — | EP | disclosed |