Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 19/20 | 0.51 |
| ▸ | CXCR1 | P25024 | 15/20 | 0.51 |
| ▸ | CCR6 | P51684 | 1/20 | 0.49 |
| ▸ | CCR7 | P32248 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13407251 | 1.00 | CXCR2 (0.51) | CXCR2CXCR1CCR6CCR7 | |
| SCHEMBL13947945 | 0.94 | CXCR2 (0.51) | CXCR2CXCR1CCR6CCR7 | |
| SCHEMBL13407348 | 0.92 | CXCR2 (0.49) | CXCR2CXCR1CCR6CCR7 | |
| SCHEMBL13407232 | 0.89 | CXCR2 (0.53) | CXCR2CXCR1CCR6 | |
| SCHEMBL13407234 | 0.89 | CCR6 (0.54) | CXCR2CXCR1CCR6CCR7 | |
| SCHEMBL13407252 | 0.88 | CCR6 (0.51) | CXCR2CXCR1CCR6CCR7 | |
| SCHEMBL13407231 | 0.87 | CCR6 (0.49) | CXCR2CXCR1CCR6CCR7 | |
| SCHEMBL13405688 | 0.86 | CCR6 (0.66) | CXCR2CXCR1CCR6CCR7 | |
| SCHEMBL13407346 | 0.85 | CXCR2 (0.68) | CXCR2CXCR1CCR6 | |
| SCHEMBL13407352 | 0.85 | CCR6 (0.53) | CXCR2CXCR1CCR6CCR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1551818-B1 | THIADIAZOLEDIOXIDES AND THIADIAZOLEOXIDES AS CXC- AND CC-CHEMOKINE RECEPTOR LIGANDS | SCHERING CORP (US) | 2009-02-04 | — | — | EP | disclosed |