Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 17/20 | 0.43 |
| ▸ | CXCR1 | P25024 | 13/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13207528 | 0.81 | CXCR2 (0.50) | CXCR2CXCR1MAPTHPGDMEN1 | |
| SCHEMBL13207531 | 0.79 | CCR6 (0.54) | CXCR2CXCR1 | |
| SCHEMBL13207529 | 0.79 | HPGD (0.53) | CXCR2CXCR1MAPTHPGDMEN1 | |
| SCHEMBL13207266 | 0.79 | CXCR2 (0.63) | CXCR2CXCR1 | |
| SCHEMBL13207519 | 0.78 | CXCR1 (0.64) | CXCR2CXCR1 | |
| SCHEMBL13207530 | 0.78 | CXCR2 (0.46) | CXCR2CXCR1MAPTHPGDMEN1 | |
| SCHEMBL13206753 | 0.77 | CXCR2 (0.45) | CXCR2CXCR1MAPTHPGDMEN1 | |
| SCHEMBL13207520 | 0.77 | CXCR1 (0.58) | CXCR2CXCR1 | |
| SCHEMBL13207527 | 0.76 | CXCR2 (0.62) | CXCR2CXCR1 | |
| SCHEMBL13207521 | 0.76 | CXCR2 (0.49) | CXCR2CXCR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1551818-B1 | THIADIAZOLEDIOXIDES AND THIADIAZOLEOXIDES AS CXC- AND CC-CHEMOKINE RECEPTOR LIGANDS | SCHERING CORP (US) | 2009-02-04 | — | — | EP | disclosed |