Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 12/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13947842 | 0.89 | CXCR2 (0.39) | CCR6CXCR2CXCR1 | |
| SCHEMBL13207222 | 0.89 | CXCR2 (0.45) | CCR6CXCR2LMNAGAACXCR1 | |
| SCHEMBL13947994 | 0.87 | CXCR2 (0.40) | CCR6CXCR2LMNAGAACXCR1 | |
| SCHEMBL13207227 | 0.85 | CXCR2 (0.38) | CCR6CXCR2LMNAGAACXCR1 | |
| SCHEMBL13207212 | 0.84 | CXCR2 (0.39) | CCR6CXCR2LMNAGAACXCR1 | |
| SCHEMBL13207214 | 0.84 | CCR6 (0.51) | CCR6CXCR2CXCR1 | |
| SCHEMBL13947933 | 0.79 | CXCR2 (0.39) | CCR6CXCR2 | |
| SCHEMBL13207960 | 0.79 | CXCR1 (0.48) | CCR6CXCR2LMNACXCR1 | |
| SCHEMBL13207229 | 0.79 | CXCR2 (0.42) | CCR6CXCR2GAACXCR1 | |
| SCHEMBL13207226 | 0.79 | KMT2A (0.38) | CCR6CXCR2LMNAGAACXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1551818-B1 | THIADIAZOLEDIOXIDES AND THIADIAZOLEOXIDES AS CXC- AND CC-CHEMOKINE RECEPTOR LIGANDS | SCHERING CORP (US) | 2009-02-04 | — | — | EP | disclosed |