Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9121212 | 0.82 | TAAR1 (0.52) | LMNACHRM2ADRA2BADRA2CCHRM3 | |
| SCHEMBL6207044 | 0.82 | S1PR2 (0.46) | S1PR2S1PR1S1PR3LPAR2PTGER2 | |
| SCHEMBL13232166 | 0.82 | S1PR2 (0.46) | S1PR2S1PR1S1PR3LPAR2LMNA | |
| SCHEMBL5672614 | 0.80 | S1PR2 (0.44) | S1PR2S1PR1S1PR3LPAR2LMNA | |
| SCHEMBL12420337 | 0.80 | S1PR2 (0.48) | S1PR2S1PR1S1PR3LPAR2PTGER2 | |
| SCHEMBL23588163 | 0.80 | AOC3 (0.50) | S1PR2S1PR1S1PR3LPAR2LMNA | |
| SCHEMBL8102586 | 0.80 | AOC3 (0.50) | S1PR2S1PR1S1PR3LPAR2PTGER2 | |
| SCHEMBL3945304 | 0.80 | S1PR2 (0.44) | S1PR2S1PR1S1PR3LPAR2PTGER2 | |
| SCHEMBL14717561 | 0.80 | S1PR2 (0.48) | S1PR2S1PR1S1PR3LPAR2PTGER2 | |
| SCHEMBL12087597 | 0.80 | HIF1A (0.52) | S1PR2S1PR1S1PR3LPAR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1716113-B1 | EP2- RECEPTOR AGONISTS | ASTERAND UK LTD (GB) | 2009-02-25 | — | — | EP | disclosed |