Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 8/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | SHBG | P04278 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13951896 | 0.89 | STS (0.45) | STSCYP19A1HSD17B1AKR1C3HSD17B10 | |
| SCHEMBL13951898 | 0.87 | STS (0.48) | STSCYP19A1HSD17B1AKR1C3HSD17B10 | |
| SCHEMBL13951899 | 0.86 | STS (0.43) | STSCYP19A1HSD17B1AKR1C3HSD17B10 | |
| SCHEMBL14048591 | 0.85 | STS (0.50) | STSCYP19A1HSD17B1AKR1C3HSD17B10 | |
| SCHEMBL13951923 | 0.79 | STS (0.72) | STSCYP19A1HSD17B1HSD17B10AKR1B10 | |
| SCHEMBL14048586 | 0.75 | STS (0.66) | STSCYP19A1HSD17B1AKR1C3HSD17B10 | |
| SCHEMBL13951902 | 0.75 | STS (0.47) | STSCYP19A1HSD17B1AKR1C3HSD17B10 | |
| SCHEMBL13951901 | 0.73 | AKR1C3 (0.40) | STSCYP19A1AKR1C3HSD17B10TSHR | |
| SCHEMBL5502437 | 0.73 | HSD17B10 (0.67) | STSCYP19A1HSD17B1AKR1C3HSD17B10 | |
| SCHEMBL14048588 | 0.73 | HSD17B10 (0.67) | STSCYP19A1HSD17B1AKR1C3HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2147014-B1 | 17ALPHA-SUBSTITUTED STEROIDS AS SYSTEMIC ANTIANDROGENS AND SELECTIVE ANDROGEN RECEPTOR MODULATORS | ENDORECH INC (CA) | 2016-02-17 | — | — | EP | disclosed |
| US-20090042844-A1 | 17ALPHA-SUBSTITUTED STEROIDS AS SYSTEMIC ANTIANDROGENS AND SELECTIVE ANDROGEN RECEPTOR MODULATORS | ENDORECHERCHE, INC. | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042844-A1 | 17ALPHA-SUBSTITUTED STEROIDS AS SYSTEMIC ANTIANDROGENS AND SELECTIVE ANDROGEN RECEPTOR MODULATORS | AR, NR5A1, SRD5A1 | STS 142/4885CYP19A1 8/4885HSD17B1 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.