Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 15/20 | 0.50 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30291860 | 0.86 | STS (0.65) | STS | |
| SCHEMBL13952013 | 0.86 | STS (0.65) | STS | |
| SCHEMBL13952156 | 0.84 | STS (0.56) | STSESR1ABCB11CYP19A1ESR2 | |
| SCHEMBL13952017 | 0.83 | STS (0.56) | STS | |
| SCHEMBL13952148 | 0.82 | STS (0.56) | STSESR1ABCB11CYP19A1ESR2 | |
| SCHEMBL13952015 | 0.82 | STS (0.54) | STS | |
| SCHEMBL13952014 | 0.81 | STS (0.53) | STS | |
| SCHEMBL13951924 | 0.79 | STS (0.69) | STS | |
| SCHEMBL13951951 | 0.77 | STS (0.59) | STS | |
| SCHEMBL13951888 | 0.77 | STS (0.56) | STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090042844-A1 | 17ALPHA-SUBSTITUTED STEROIDS AS SYSTEMIC ANTIANDROGENS AND SELECTIVE ANDROGEN RECEPTOR MODULATORS | ENDORECHERCHE, INC. | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042844-A1 | 17ALPHA-SUBSTITUTED STEROIDS AS SYSTEMIC ANTIANDROGENS AND SELECTIVE ANDROGEN RECEPTOR MODULATORS | AR, NR5A1, SRD5A1 | STS 142/4885ESR1 218/4885ABCB11 905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.