Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PANK3 | Q9H999 | 8/20 | 0.49 |
| ▸ | FLT3 | P36888 | 8/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3882199 | 0.86 | FLT3 (0.61) | PANK3FLT3 | |
| SCHEMBL14596996 | 0.86 | FLT3 (0.61) | PANK3FLT3 | |
| SCHEMBL13956287 | 0.86 | FLT3 (0.61) | PANK3FLT3 | |
| SCHEMBL13751779 | 0.77 | FLT3 (0.73) | PANK3FLT3 | |
| SCHEMBL3888652 | 0.77 | FLT3 (0.73) | PANK3FLT3 | |
| SCHEMBL26502429 | 0.70 | PANK3 (0.59) | PANK3AKT1 | |
| SCHEMBL21406473 | 0.69 | PANK3 (0.67) | PANK3AKT1MEN1KMT2A | |
| SCHEMBL26501618 | 0.68 | PANK3 (0.76) | PANK3POLBMEN1KMT2A | |
| SCHEMBL21423846 | 0.67 | PANK3 (0.72) | PANK3 | |
| SCHEMBL21423676 | 0.67 | PANK3 (1.00) | PANK3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1898917-B1 | AMINOPYRIMIDINES AS KINASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2009-01-14 | — | — | EP | disclosed |