Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 8/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.35 |
| ▸ | CSF1R | P07333 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13959996 | 0.85 | CSF1R (0.37) | ABL1BRAFKITCSF1REGFR | |
| SCHEMBL13961067 | 0.84 | TEK (0.40) | BRAFCSF1R | |
| SCHEMBL13960588 | 0.82 | MAPT (0.35) | ABL1BRAFMCHR1KITCSF1R | |
| SCHEMBL13960357 | 0.82 | CSF1R (0.48) | ABL1BRAFKITCSF1RGPR142 | |
| SCHEMBL13960600 | 0.81 | ABL1 (0.48) | ABL1BRAF | |
| SCHEMBL13960583 | 0.81 | BRAF (0.40) | ABL1BRAFKITCSF1REGFR | |
| SCHEMBL13960605 | 0.81 | LCK (0.41) | ABL1BRAFKITCSF1R | |
| SCHEMBL13960848 | 0.79 | DDR2 (0.50) | ABL1BRAFKIT | |
| SCHEMBL13960475 | 0.79 | BRAF (0.46) | ABL1BRAFKITEGFR | |
| SCHEMBL13959990 | 0.78 | BRAF (0.45) | ABL1BRAFKITEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009003999-A2 | CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-01-08 | — | — | WO | disclosed |