Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 4/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8163204 | 1.00 | FFAR3 (0.43) | FFAR3LCKFYNPTGS1AKR1C3 | |
| SCHEMBL133954 | 1.00 | — | — | |
| SCHEMBL338643 | 1.00 | FFAR3 (0.43) | FFAR3LCKFYNPTGS1AKR1C3 | |
| SCHEMBL15042 | 1.00 | — | — | |
| SCHEMBL18814 | 1.00 | — | — | |
| SCHEMBL871351 | 1.00 | FFAR3 (0.43) | FFAR3LCKFYNPTGS1AKR1C3 | |
| Hydrochloric Acid SCHEMBL3838334 | 0.96 | — | — | |
| SCHEMBL134938 | 0.96 | — | — | |
| SCHEMBL1021693 | 0.96 | — | — | |
| SCHEMBL1615808 | 0.96 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0633279-A1 | Preparation of ether carboxylates | ALBRIGHT & WILSON UK LIMITED (GB) | 1995-01-11 | — | — | EP | claimed |
| EP-2807263-A1 | PROCESS FOR THE PREPARATION OF INGENOL-3-ANGELATE | Leo Laboratories Limited (IE) | 2014-12-03 | — | — | EP | disclosed |
| WO-2013110753-A1 | PROCESS FOR THE PREPARATION OF INGENOL-3-ANGELATE | LEO PHARMA A/S (DK) | 2013-08-01 | — | — | WO | disclosed |
| EP-2349260-A1 | JANUS KINASE INHIBITORS FOR TREATMENT OF DRY EYE AND OTHER EYE RELATED DISEASES | Incyte Corporation (US) | 2011-08-03 | — | — | EP | disclosed |
| EP-2288610-A1 | AZETIDINE AND CYCLOBUTANE DERIVATIVES AS JAK INHIBITORS | Incyte Corporation (US) | 2011-03-02 | — | — | EP | disclosed |