Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 13/20 | 0.80 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.66 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2929238 | 0.90 | S1PR1 (0.82) | S1PR1S1PR5ALOX15S1PR3S1PR4 | |
| SCHEMBL13416529 | 0.90 | S1PR1 (1.00) | S1PR1S1PR5ALOX15S1PR3S1PR4 | |
| SCHEMBL2935270 | 0.89 | S1PR1 (0.80) | S1PR1S1PR5ALOX15S1PR3S1PR4 | |
| SCHEMBL13417142 | 0.89 | S1PR1 (0.80) | S1PR1S1PR5ALOX15S1PR3S1PR4 | |
| SCHEMBL1413283 | 0.84 | S1PR1 (0.88) | S1PR1S1PR5ALOX15S1PR3S1PR4 | |
| SCHEMBL3821552 | 0.83 | S1PR1 (0.74) | S1PR1S1PR5ALOX15S1PR3S1PR4 | |
| SCHEMBL27937903 | 0.83 | S1PR1 (0.70) | S1PR1S1PR5ALOX15S1PR3S1PR4 | |
| SCHEMBL3826033 | 0.83 | S1PR1 (0.80) | S1PR1S1PR5ALOX15S1PR3S1PR4 | |
| SCHEMBL4619556 | 0.81 | S1PR1 (0.64) | S1PR1S1PR5ALOX15S1PR3S1PR4 | |
| SCHEMBL29389224 | 0.81 | S1PR1 (1.00) | S1PR1S1PR5ALOX15S1PR3S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7479504-B2 | Edg receptor agonists | MERCK & CO., INC. (US) | 2009-01-20 | — | — | US | disclosed |