Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4923021 | 0.90 | BACE1 (0.35) | BACE1SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL4923022 | 0.90 | BACE1 (0.35) | BACE1SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL4923027 | 0.90 | BACE1 (0.35) | BACE1SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL31644659 | 0.86 | BACE1 (0.34) | BACE1SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL16830150 | 0.86 | BACE1 (0.36) | BACE1SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL25521007 | 0.82 | BACE1 (0.35) | BACE1SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL31162893 | 0.82 | BACE1 (0.35) | BACE1SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL23533062 | 0.81 | BACE1 (0.39) | BACE1SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL22283669 | 0.81 | BACE1 (0.34) | BACE1SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL16328030 | 0.81 | BACE1 (0.34) | BACE1SMYD2CYP3A4HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4646197-A2 | ORGANIC COMPOUNDS AS NLRP3 INHIBITORS | Kodiak Sciences Inc. (US) | 2025-11-12 | — | — | EP | disclosed |
| WO-2024148029-A2 | ORGANIC COMPOUNDS AS NLRP3 INHIBITORS | KODIAK SCIENCES INC. (US) | 2024-07-11 | — | — | WO | disclosed |
| EP-2288610-A1 | AZETIDINE AND CYCLOBUTANE DERIVATIVES AS JAK INHIBITORS | Incyte Corporation (US) | 2011-03-02 | — | — | EP | disclosed |
| WO-2009114512-A1 | AZETIDINE AND CYCLOBUTANE DERIVATIVES AS JAK INHIBITORS | INCYTE CORPORATION (US) | 2009-09-17 | — | — | WO | disclosed |