Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29265310 | 0.80 | CYP2D6 (0.49) | CYP2D6CHRM2CHRM1SLC6A2ADRA1A | |
| SCHEMBL27276181 | 0.77 | CYP2D6 (0.46) | CYP2D6CHRM2CHRM1SLC6A2ADRA1A | |
| SCHEMBL14415670 | 0.72 | HTR2A (0.55) | CYP2D6CHRM2CHRM1SLC6A2ADRA1A | |
| SCHEMBL11834975 | 0.71 | CYP2D6 (0.59) | CYP2D6CHRM2CHRM1SLC6A2ADRA1A | |
| SCHEMBL13319990 | 0.71 | CYP2D6 (0.46) | CYP2D6CHRM2CHRM1SLC6A2ADRA1A | |
| SCHEMBL27512963 | 0.71 | RET (0.38) | CYP2D6CHRM2CHRM1SLC6A2ADRA1A | |
| SCHEMBL12510835 | 0.68 | SLC6A4 (0.42) | CYP2D6CHRM2CHRM1SLC6A2ADRA1A | |
| SCHEMBL7001557 | 0.67 | HTR2A (0.58) | CYP2D6CHRM2CHRM1SLC6A2ADRA1A | |
| SCHEMBL8664813 | 0.67 | CYP2D6 (0.43) | CYP2D6CHRM2CHRM1SLC6A2ADRA1A | |
| SCHEMBL13208764 | 0.66 | CYP1A2 (0.52) | CYP2D6CHRM2CHRM1SLC6A2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009015207-A1 | SMALL MOLECULES FOR THE PROTECTION OF PANCREATIC CELLS | ZOLTAN LABORATORIES LLC (US) | 2009-01-29 | — | — | WO | disclosed |
| WO-2008118164-A1 | COMPOUNDS TO PROMOTE REGENERATION OF BONE MARROW | ZOLTAN LABORATORIES LLC (US) | 2008-10-02 | — | — | WO | disclosed |