Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COMT | P21964 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.43 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 4/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2359843 | 0.93 | COMT (0.56) | COMTESR1ESR2GRIA1CACNG8 | |
| SCHEMBL13965072 | 0.87 | COMT (0.48) | COMTESR1ESR2GRIA1CACNG8 | |
| SCHEMBL13965114 | 0.86 | COMT (0.45) | COMTESR1ESR2GRIA1CACNG8 | |
| SCHEMBL13964961 | 0.86 | COMT (0.47) | COMTESR1ESR2GRIA1CACNG8 | |
| SCHEMBL13964986 | 0.85 | KDM4E (0.51) | COMTESR1ESR2GRIA1CACNG8 | |
| SCHEMBL21081232 | 0.85 | ESR1 (0.50) | COMTESR1ESR2GRIA1CACNG8 | |
| SCHEMBL13965095 | 0.85 | KDM4E (0.50) | COMTESR1ESR2GRIA1CACNG8 | |
| SCHEMBL14298069 | 0.85 | ESR1 (0.42) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL13965069 | 0.85 | ESR1 (0.49) | COMTESR1ESR2GRIA1CACNG8 | |
| SCHEMBL22963691 | 0.84 | ESR1 (0.44) | COMTESR1ESR2GRIA1CACNG8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9741944-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2017-08-22 | — | — | US | disclosed |
| US-20170012221-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-01-12 | — | — | US | disclosed |
| US-9409883-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2016-08-09 | — | — | US | disclosed |
| US-20120292571-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120292571-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | EPCAM, SLC39A3, L1CAM | COMT 334/4885ESR1 132/4885ESR2 609/4885 |
| US-20170012221-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | EPCAM, SLC39A3, L1CAM | COMT 334/4885ESR1 132/4885ESR2 609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.