⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28744105 | 0.79 | DPP4 (0.31) | — | |
| SCHEMBL11496222 | 0.79 | — | — | |
| SCHEMBL16939151 | 0.76 | DPP4 (0.32) | — | |
| SCHEMBL3723085 | 0.71 | SLC7A5 (0.48) | — | |
| SCHEMBL23643845 | 0.69 | TP53 (0.32) | — | |
| SCHEMBL8461804 | 0.69 | TP53 (0.32) | — | |
| SCHEMBL268874 | 0.69 | — | — | |
| SCHEMBL959198 | 0.67 | — | — | |
| SCHEMBL7064786 | 0.67 | — | — | |
| SCHEMBL1267257 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230340012-A1 | NATURAL AND SYNTHETIC COMPOUNDS FOR TREATING CANCER AND OTHER DISEASES | PACIFIC ARROW LTD (CN) | 2023-10-26 | — | — | US | disclosed |
| US-20230159436-A1 | APPLICATIONS OF AMIDE ANALOGS OF TRITERPENES IN CURES OF CANCER AND OTHER DISEASES | PACIFIC ARROW LTD (CN) | 2023-05-25 | — | — | US | disclosed |
| US-20200199172-A1 | NATURAL AND SYNTHETIC COMPOUNDS FOR TREATING CANCER AND OTHER DISEASES | PACIFIC ARROW LTD (CN) | 2020-06-25 | — | — | US | disclosed |
| US-10590163-B2 | Natural and synthetic compounds for treating cancer and other diseases | PACIFIC ARROW LIMITED (CN) | 2020-03-17 | — | — | US | disclosed |
| WO-2018167677-A1 | NOVEL DITHIOLANE COMPOUND OR A SALT OR AN N-OXIDE AND USE THEREOF | OAT & IIL INDIA LABORATORIES PRIVATE LIMITED (IN) | 2018-09-20 | — | — | WO | disclosed |
| WO-2018138692-A1 | NOVEL FUNGICIDAL CARBAMATE COMPOUNDS | INSECTICIDES (INDIA) LIMITED (IN) | 2018-08-02 | — | — | WO | disclosed |
| US-20170267714-A1 | NATURAL AND SYNTHETIC COMPOUNDS FOR TREATING CANCER AND OTHER DISEASES | PACIFIC ARROW LTD (CN) | 2017-09-21 | — | — | US | disclosed |
| US-20170022246-A1 | NATURAL AND SYNTHETIC COMPOUNDS FOR TREATING CANCER AND OTHER DISEASES | PACIFIC ARROW LTD (CN) | 2017-01-26 | — | — | US | disclosed |
| US-9499577-B2 | Natural and synthetic compounds for treating cancer and other diseases | PACIFIC ARROW LTD (CN) | 2016-11-22 | — | — | US | disclosed |
| US-9434677-B2 | Natural and synthetic compounds for treating cancer and other diseases | PACIFIC ARROW LIMITED (HK) | 2016-09-06 | — | — | US | disclosed |
| EP-2336315-A2 | Enzymatic encoding methods for efficient synthesis of large libraries | Nuevolution A/S (DK) | 2011-06-22 | — | — | EP | disclosed |
| US-20100317630-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS MGLU5 ANTAGONISTS | RECORDATI IRELAND LIMITED (IE) | 2010-12-16 | — | — | US | disclosed |
| WO-2010086350-A1 | 9-DEOXO- 9A-METHYL- 9A- AZA- 9A-H0M0ERYTHR0MYCIN A DERIVATIVES FOR THE TREATMENT OF NEUTROPHIL DOMINATED INFLAMMATORY DISEASES | GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. (HR) | 2010-08-05 | — | — | WO | disclosed |
| US-20100137582-A1 | N-PYRIDYLPIPERIDINE COMPOUND, METHOD FOR PRODUCING THE SAME, AND PEST CONTROL AGENT | OTSUKA CHEMICAL CO., LTD. (JP) | 2010-06-03 | — | — | US | disclosed |
| US-7560550-B2 | Method for the production of OH protected[4-(2.6-diamino-9H-purine-9-yl)-1.3-dioxolane-2-yl]methanol derivatives | RFS PHARMA, LLC (US) | 2009-07-14 | — | — | US | disclosed |
| US-20070270436-A1 | NOVEL AMINO- AND IMINO-ALKYLPIPERAZINES | RECORDATI IRELAND LIMITED (IE) | 2007-11-22 | — | — | US | disclosed |
| EP-1648894-B1 | METHOD FOR THE PRODUCTION OF OH PROTECTED [4-(2.6-DIAMINO-9H-PURINE-9-YL)- 1.3-DIOXOLANE-2-YL]METHANOL DERIVATIVES | WACKER CHEMIE AG (DE) | 2007-09-12 | — | — | EP | disclosed |
| US-20060211855-A1 | Method for the production of oh protected{4-(2.6-diamino-9h-purine-9-yl)-1.3-dioxolane-2-yl] methanol derivatives | WACKER CHEMIE AG (DE) | 2006-09-21 | — | — | US | disclosed |
| EP-1648894-A1 | METHOD FOR THE PRODUCTION OF OH PROTECTED [4-(2.6-DIAMINO-9H-PURINE-9-YL)- 1.3-DIOXOLANE-2-YL]METHANOL DERIVATIVES | Wacker Chemie AG (DE) | 2006-04-26 | — | — | EP | disclosed |
| WO-2005012302-A1 | METHOD FOR THE PRODUCTION OF OH PROTECTED [4-(2.6-DIAMINO-9H-PURINE-9-YL)- 1.3-DIOXOLANE-2-YL]METHANOL DERIVATIVES | WACKER CHEMIE AG (DE) | 2005-02-10 | — | — | WO | disclosed |