Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10113454 | 0.97 | MAPT (0.48) | MAPTGAAALDH1A1KDM4ETP53 | |
| SCHEMBL10113622 | 0.97 | MAPT (0.48) | MAPTGAAALDH1A1KDM4ETP53 | |
| SCHEMBL10115047 | 0.97 | MAPT (0.48) | MAPTGAAALDH1A1KDM4ETP53 | |
| SCHEMBL10133426 | 0.88 | MAPT (0.50) | MAPTGAAALDH1A1KDM4ETP53 | |
| SCHEMBL10114435 | 0.88 | MAPT (0.50) | MAPTGAAALDH1A1KDM4ETP53 | |
| SCHEMBL10133428 | 0.87 | MAPT (0.48) | MAPTALDH1A1KDM4ETP53SMN1; SMN2 | |
| SCHEMBL10114424 | 0.87 | MAPT (0.48) | MAPTALDH1A1KDM4ETP53SMN1; SMN2 | |
| SCHEMBL10134478 | 0.85 | KDM4E (0.44) | MAPTGAAALDH1A1KDM4ETP53 | |
| SCHEMBL10134481 | 0.85 | KDM4E (0.44) | MAPTGAAALDH1A1KDM4ETP53 | |
| SCHEMBL10115019 | 0.85 | KDM4E (0.44) | MAPTGAAALDH1A1KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014285-A1 | NPYY5 antagonists | Shionogi&Co., Ltd. (JP) | 2009-01-14 | — | — | EP | disclosed |