Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15480431 | 0.79 | POLB (0.66) | POLBRAB9AHDAC3HDAC1NCOR2 | |
| SCHEMBL10115474 | 0.78 | HDAC3 (0.56) | POLBRAB9AHDAC3HDAC1NCOR2 | |
| SCHEMBL4133118 | 0.76 | POLB (0.58) | POLBRAB9AHDAC3HDAC1TP53 | |
| SCHEMBL13973255 | 0.75 | HDAC4 (0.57) | HDAC3HDAC1NCOR2BRD4 | |
| SCHEMBL6267767 | 0.74 | POLB (0.59) | POLBRAB9AHDAC3HDAC1NCOR2 | |
| SCHEMBL15480422 | 0.74 | HDAC1 (0.63) | POLBRAB9AHDAC3HDAC1NCOR2 | |
| SCHEMBL31203495 | 0.74 | HDAC3 (0.54) | POLBRAB9AHDAC3HDAC1NCOR2 | |
| SCHEMBL17293747 | 0.73 | POLB (0.58) | POLBRAB9AHDAC3HDAC1NCOR2 | |
| SCHEMBL6274364 | 0.73 | POLB (0.58) | POLBRAB9AHDAC3HDAC1NCOR2 | |
| SCHEMBL30944763 | 0.73 | POLB (0.58) | POLBRAB9AHDAC3HDAC1NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014285-A1 | NPYY5 antagonists | Shionogi&Co., Ltd. (JP) | 2009-01-14 | — | — | EP | disclosed |