Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | EIF4E | P06730 | 4/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2198055 | 0.86 | POLR1A (0.41) | RAB9APKMALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2198058 | 0.74 | POLR1A (0.41) | RAB9APKMALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2230472 | 0.73 | POLR1A (0.41) | RAB9APKMALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL13973492 | 0.73 | KDM5B (0.42) | KDM5BHRH4POLBMAPK1HSD17B10 | |
| SCHEMBL2199991 | 0.69 | HTR2A (0.43) | RAB9AALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL2202912 | 0.69 | KDM1A (0.42) | RAB9APKMALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL13973495 | 0.69 | GRM5 (0.48) | KDM5BSMN1; SMN2 | |
| SCHEMBL13973493 | 0.68 | CNR1 (0.43) | HPGDKDM4EHSD17B10 | |
| SCHEMBL2197341 | 0.68 | MKNK1 (0.51) | RAB9AALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL2200016 | 0.67 | JAK1 (0.41) | ALDH1A1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009013211-A2 | NEW PYRAZOL DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2009-01-29 | — | — | WO | disclosed |