Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 20/20 | 0.56 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.48 |
| ▸ | CDK1 | P06493 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | PIM1 | P11309 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CDK2 | P24941 | 2/20 | 0.48 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.48 |
| ▸ | CLK2 | P49760 | 2/20 | 0.48 |
| ▸ | GSK3A | P49840 | 2/20 | 0.48 |
| ▸ | GSK3B | P49841 | 2/20 | 0.48 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.48 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.48 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.48 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.48 |
| ▸ | STK3 | Q13188 | 2/20 | 0.48 |
| ▸ | CAMK2B | Q13554 | 2/20 | 0.48 |
| ▸ | CAMK2G | Q13555 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13978062 | 0.93 | PRKCQ (0.46) | PRKCQMAP4K4CDK1CYP3A4CYP2D6 | |
| SCHEMBL13978067 | 0.90 | PRKCQ (0.45) | PRKCQMAP4K4CDK1CYP3A4CYP2D6 | |
| SCHEMBL13978289 | 0.88 | PRKCQ (0.46) | PRKCQMAP4K4CDK1CYP3A4CYP2D6 | |
| SCHEMBL13978288 | 0.88 | PRKCQ (0.41) | PRKCQMAP4K4CDK1CYP3A4CYP2D6 | |
| SCHEMBL13978061 | 0.87 | PRKCQ (0.58) | PRKCQMAP4K4CDK1CYP3A4CYP2D6 | |
| SCHEMBL13978376 | 0.86 | PRKCQ (0.64) | PRKCQMAP4K4CDK1CYP3A4CYP2D6 | |
| SCHEMBL13978290 | 0.85 | PRKCQ (0.40) | PRKCQPIM1MAPK9 | |
| SCHEMBL13978287 | 0.83 | PRKCQ (0.51) | PRKCQMAP4K4CDK1CYP3A4CYP2D6 | |
| SCHEMBL13978066 | 0.83 | PRKCQ (0.50) | PRKCQMAP4K4CDK1CYP3A4CYP2D6 | |
| SCHEMBL13978368 | 0.82 | PRKCQ (0.61) | PRKCQMAP4K4CDK1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012156467-A1 | NOVEL PKC INHIBITORS | AMAKEM NV (BE) | 2012-11-22 | — | — | WO | disclosed |