Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 6/20 | 0.45 |
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.45 |
| ▸ | NNMT | P40261 | 3/20 | 0.45 |
| ▸ | PCMT1 | P22061 | 2/20 | 0.45 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.45 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.45 |
| ▸ | SETD2 | Q9BYW2 | 2/20 | 0.45 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.45 |
| ▸ | TRDMT1 | O14717 | 2/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | RNMT | O43148 | 1/20 | 0.45 |
| ▸ | INMT | O95050 | 1/20 | 0.45 |
| ▸ | TPMT | P51580 | 1/20 | 0.45 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.45 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.45 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.45 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.45 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.45 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13976309 | 0.87 | NSD2 (0.55) | NSD2SETD7NNMTPCMT1DOT1L | |
| SCHEMBL13966923 | 0.84 | NSD2 (0.55) | NSD2SETD7NNMTPCMT1DOT1L | |
| SCHEMBL13966927 | 0.84 | NSD2 (0.55) | NSD2SETD7NNMTPCMT1DOT1L | |
| SCHEMBL13966928 | 0.83 | NSD2 (0.54) | NSD2SETD7NNMTPCMT1DOT1L | |
| SCHEMBL17049404 | 0.83 | NSD2 (0.54) | NSD2SETD7NNMTPCMT1DOT1L | |
| SCHEMBL13966933 | 0.82 | NSD2 (0.53) | NSD2SETD7NNMTPCMT1DOT1L | |
| SCHEMBL13966930 | 0.82 | NSD2 (0.53) | NSD2SETD7NNMTPCMT1DOT1L | |
| SCHEMBL13976377 | 0.81 | NSD2 (0.55) | NSD2SETD7NNMTPCMT1DOT1L | |
| SCHEMBL17250752 | 0.80 | NSD2 (0.56) | NSD2SETD7NNMTPCMT1DOT1L | |
| SCHEMBL17250753 | 0.80 | NSD2 (0.56) | NSD2SETD7NNMTPCMT1DOT1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012159072-A2 | FLUORESCENT MOLECULAR PROBES FOR USE IN ASSAYS THAT MEASURE TEST COMPOUND COMPETITIVE BINDING WITH SAM-UTILIZING PROTEINS | CAYMAN CHEMICAL COMPANY, INCORPORATED (US) | 2012-11-22 | — | — | WO | disclosed |