Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.40 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.38 |
| ▸ | KCNB1 | Q14721 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12444347 | 0.97 | ERAP2 (0.43) | MMP2ERAP2LNPEPERAP1FFAR1 | |
| SCHEMBL10199226 | 0.97 | ERAP2 (0.43) | MMP2ERAP2LNPEPERAP1FFAR1 | |
| SCHEMBL12444349 | 0.97 | ERAP2 (0.43) | MMP2ERAP2LNPEPERAP1FFAR1 | |
| SCHEMBL10199137 | 0.97 | ERAP2 (0.43) | MMP2ERAP2LNPEPERAP1FFAR1 | |
| SCHEMBL19219773 | 0.97 | ERAP2 (0.42) | MMP2ERAP2LNPEPERAP1FFAR1 | |
| SCHEMBL21371614 | 0.97 | ERAP2 (0.42) | MMP2ERAP2LNPEPERAP1FFAR1 | |
| SCHEMBL21371982 | 0.97 | ERAP2 (0.42) | MMP2ERAP2LNPEPERAP1FFAR1 | |
| SCHEMBL13978361 | 0.94 | ERAP2 (0.41) | MMP2ERAP2LNPEPERAP1FFAR1 | |
| SCHEMBL10199113 | 0.94 | ERAP2 (0.40) | MMP2ERAP2LNPEPERAP1FFAR1 | |
| SCHEMBL12515263 | 0.93 | NPY4R (0.37) | MMP2ERAP2LNPEPERAP1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012158672-A2 | COMPOUNDS FOR USE IN TREATMENT OF MUCOSITIS | POLYMEDIX, INC. (US) | 2012-11-22 | — | — | WO | disclosed |