Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 4/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | TACR2 | P21452 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | DRD5 | P21918 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | TSPO | P30536 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13980407 | 0.90 | CHRM1 (0.51) | CHRM1CHRM5CHRM2CHRM4CHRM3 | |
| SCHEMBL1835311 | 0.78 | CHRM1 (0.61) | CHRM1CHRM5CHRM2CHRM4CHRM3 | |
| SCHEMBL3630837 | 0.77 | CHRM1 (0.59) | CHRM1CHRM5CHRM2CHRM4CHRM3 | |
| SCHEMBL1833174 | 0.75 | CHRM1 (0.58) | CHRM1CHRM5CHRM2CHRM4CHRM3 | |
| SCHEMBL13980480 | 0.75 | CHRM2 (0.50) | CHRM1CHRM5CHRM2CHRM4CHRM3 | |
| Hydrochloric Acid SCHEMBL1835308 | 0.75 | CHRM1 (0.57) | CHRM1CHRM5CHRM2CHRM4CHRM3 | |
| SCHEMBL13980481 | 0.75 | CHRM1 (0.63) | CHRM1CHRM5CHRM2CHRM4CHRM3 | |
| SCHEMBL1833085 | 0.75 | CHRM1 (0.63) | CHRM1CHRM5CHRM2CHRM4CHRM3 | |
| SCHEMBL12658441 | 0.74 | CHRM1 (0.53) | CHRM1CHRM5CHRM2CHRM4CHRM3 | |
| SCHEMBL1833497 | 0.74 | CHRM1 (0.56) | CHRM1CHRM5CHRM2CHRM4CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1997805-A1 | Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans | Commissariat à l'Energie Atomique (FR) | 2008-12-03 | — | — | EP | disclosed |