Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 11/20 | 0.79 |
| ▸ | ESR2 | Q92731 | 11/20 | 0.79 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.64 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.64 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.64 |
| ▸ | SHBG | P04278 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1119325 | 0.88 | ESR1 (1.00) | ESR1ESR2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL10906162 | 0.80 | ESR1 (0.51) | ESR1ESR2CSNK2A2CSNK2BCSNK2A1 | |
| Iodide SCHEMBL10901962 | 0.78 | ESR1 (0.49) | ESR1ESR2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL3927613 | 0.72 | ESR1 (0.67) | ESR1ESR2SHBG | |
| SCHEMBL3922992 | 0.71 | ESR1 (1.00) | ESR1ESR2SHBG | |
| SCHEMBL3925852 | 0.71 | ESR1 (0.57) | ESR1ESR2SHBG | |
| SCHEMBL3927964 | 0.71 | ESR1 (1.00) | ESR1ESR2SHBG | |
| SCHEMBL3934323 | 0.71 | ESR1 (0.66) | ESR1ESR2SHBG | |
| SCHEMBL3928011 | 0.71 | ESR1 (1.00) | ESR1ESR2 | |
| SCHEMBL3932733 | 0.71 | ESR1 (0.68) | ESR1ESR2CSNK2A2CSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458700-B1 | SUBSTITUTED 2-PHENYL BENZOFURANS AS ESTROGENIC AGENTS | WYETH CORP (US) | 2008-12-03 | — | — | EP | disclosed |