Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.64 |
| ▸ | PPARG | P37231 | 2/20 | 0.64 |
| ▸ | FABP2 | P12104 | 1/20 | 0.64 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.64 |
| ▸ | CNR1 | P21554 | 14/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | ACHE | P22303 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10972962 | 1.00 | PPARA (0.64) | PPARAPPARGFABP2SLC22A12CNR1 | |
| SCHEMBL22221664 | 0.88 | CNR1 (0.65) | PPARAPPARGFABP2SLC22A12CNR1 | |
| SCHEMBL10970653 | 0.85 | CNR1 (0.56) | PPARAPPARGFABP2SLC22A12CNR1 | |
| SCHEMBL10968550 | 0.84 | PPARA (0.60) | PPARAPPARGFABP2SLC22A12CNR1 | |
| SCHEMBL11031297 | 0.84 | PPARA (0.60) | PPARAPPARGFABP2SLC22A12CNR1 | |
| SCHEMBL20710314 | 0.83 | PPARA (0.53) | PPARAPPARGFABP2SLC22A12CNR1 | |
| SCHEMBL31738604 | 0.83 | PPARA (0.53) | PPARAPPARGFABP2SLC22A12CNR1 | |
| SCHEMBL20703801 | 0.83 | PPARA (0.53) | PPARAPPARGFABP2SLC22A12CNR1 | |
| SCHEMBL22221490 | 0.82 | PPARA (0.63) | PPARAPPARGFABP2SLC22A12CNR1 | |
| SCHEMBL22221437 | 0.82 | PPARA (0.60) | PPARAPPARGFABP2SLC22A12CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008157537-A2 | COMPOSITIONS AND METHODS OF USE FOR TREATING OR PREVENTING LIPID RELATED DISORDERS | IRONWOOD PHARMACEUTICALS, INC (US) | 2008-12-24 | — | — | WO | disclosed |