Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | SMYD3 | Q9H7B4 | 6/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | IDE | P14735 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4097172 | 0.92 | KMT2A (0.52) | KMT2AMEN1ABCB1SMYD3HSD17B10 | |
| SCHEMBL13984103 | 0.92 | KMT2A (0.54) | KMT2AMEN1ABCB1SMYD3HSD17B10 | |
| SCHEMBL13984097 | 0.91 | KMT2A (0.50) | KMT2AMEN1ABCB1SMYD3HSD17B10 | |
| SCHEMBL4095415 | 0.91 | KMT2A (0.57) | KMT2AMEN1ABCB1SMYD3HSD17B10 | |
| SCHEMBL13984095 | 0.91 | KMT2A (0.49) | KMT2AMEN1ABCB1SMYD3HSD17B10 | |
| SCHEMBL4092356 | 0.90 | KMT2A (0.51) | KMT2AMEN1ABCB1SMYD3HSD17B10 | |
| SCHEMBL13984419 | 0.89 | KMT2A (0.48) | KMT2AMEN1ABCB1SMYD3HSD17B10 | |
| SCHEMBL13984350 | 0.89 | ABCB1 (0.49) | KMT2AMEN1ABCB1HSD17B10MAPT | |
| SCHEMBL4099459 | 0.89 | KMT2A (0.51) | KMT2AMEN1ABCB1SMYD3HSD17B10 | |
| SCHEMBL4090724 | 0.88 | KMT2A (0.55) | KMT2AMEN1ABCB1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008157500-A1 | AMINOQUINAZOLINE CANNABINOID RECEPTOR MODULATORS FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |