Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12847224 | 0.88 | HDAC1 (0.42) | MAPTKDM4EGAALMNAHTT | |
| SCHEMBL3689603 | 0.85 | HDAC6 (0.55) | MAPTKDM4EGAALMNAHTT | |
| SCHEMBL13984946 | 0.85 | MCHR1 (0.34) | HDAC6MCHR1GABRDGABRB1GABRA4 | |
| SCHEMBL701105 | 0.84 | CDK2 (0.45) | CDK2GSK3BSYK | |
| SCHEMBL12791007 | 0.82 | KDM4E (0.46) | MAPTKDM4EGAALMNAHTT | |
| SCHEMBL13985088 | 0.82 | CDK2 (0.62) | MAPTKDM4EGAALMNAHTT | |
| SCHEMBL13985033 | 0.81 | PRKD3 (0.42) | MAPTKDM4EGAALMNAHTT | |
| SCHEMBL12791301 | 0.81 | PRKD3 (0.42) | MAPTKDM4EGAALMNAHTT | |
| SCHEMBL12790466 | 0.81 | PRKD3 (0.51) | MAPTKDM4EGAALMNAHTT | |
| SCHEMBL3809864 | 0.80 | CFTR (0.56) | MAPTKDM4EGAALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009002534-A1 | IMIDAZOPYRIDINYL THIAZOLYL HISTONE DEACETYLASE INHIBITORS | GILEAD COLORADO, INC. (US) | 2008-12-31 | — | — | WO | disclosed |